You can delete the file from S3 bucket by using object.delete().
Here is the way I implemented it.
s3 = boto3.resource("s3")
obj = s3.Object("aniketbucketpython", "abcd.txt")
For more details on S3 and its capabilities, refer to https://www.youtube.com/watch?v=XjPUyGKRjZs
Hope this helps.